近三年发表的部分论文：

1 Liu HR*, Fan HQ, Gao XH, Huang XQ, Liu XJ,Liu LB, Zhou C, Tang JJ, Wang QA,Liu WK. Design, synthesis and preliminary structure–activity relationship investigation of nitrogen-containing chalcone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors: a further study based on Flavokawain B Mannich base derivatives. J Enzyme Inhib Med Chem. 2015 Jul 17:1-10. [Epub ahead of print]

2 Liu HR*, Zhou C, Fan HQ, Tang JJ, Liu LB, Gao XH, Wang QA, Liu WK. Novel Potent and Selective Acetylcholinesterase Inhibitors as Potential Drugs for the Treatment of Alzheimer’s Disease: Synthesis, Pharmacological Evaluation, and Molecular Modeling of Amino-Alkyl-Substituted Fluoro-Chalcones Derivatives.    , Chem Biol Drug Des, 2015, 86(4):517–522

3 Liu HR*, Liu XJ, Fan HQ, Tang JJ, Gao XH, Liu WK.Design, synthesis and pharmacological evaluation of chalcone　derivatives as acetylcholinesterase inhibitors. Bioorgan  Med  Chem  22 (2014) 6124–6133.

4 Liu HR, Huang XQ, Lou DH, Liu XJ, Liu WK, Wang QA*. Synthesis and acetylcholinesterase inhibitory activity of Mannich base derivatives flavokawain B. Bioorgan  Med  Chem  Lett 24 (2014) 4749–4753.

5 Liu HR*, Liu Y, Li YL, Qi MY ,Liu WK. Synthesis and biological activity of nitric oxide-releasing derivatives of ferulic acid as potential agents for the treatment of chronic kidney diseases. Med Chem. 2013;9(6):875-880.

6 Duan KK, Liu HR, Fan HQ, Zhang J, Wang QA*. Synthesis and anticholinesterase inhibitory activity of Mannich base derivatives of flavonoids.   J  Chem  Res, 2014, 38：443–446.

7 许守慧，刘浩然，娄定辉，汪秋安*. 查尔酮Mannich碱衍生物的合成与AChE抑制活性研究, 有机化学, 2014, 34:749-755.